Breaking the Wall of Viral Drug Resistance

Breaking the Wall of Viral Drug Resistance

How Bioinformatics Can Help to Improve AIDS Therapies

Streaming Video - 2012
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Significantly improving the effectiveness of drug therapy of AIDS patients, Thomas Lengauer and his collaborators have developed bioinformatical models for predicting the resistance of HIV viral variants to applied drug combinations. This 2010 Falling Walls lecture video explores how his research has led to effective AIDS therapy, especially in the later stages of the disease, when the virus has evolved to high resistance. Lengauer's prestigious honors include the Karl Heinz Beckurts Award, the Konrad-Zuse Medal of the German Informatics Society, and membership within respected science academies like acatech and Leopoldina. This computational biologist provides physicians with important software tools for diagnosis and therapy, based on large databases of clinical and virological data on HIV therapy. Decoding the building blocks of life with mathematical-statistical methods, Lengauer's work opens up new therapy options for AIDS patients for whom traditional alternatives are difficult or impossible to find.
Publisher: New York, N.Y. : Films Media Group, [2012], c2010.
Characteristics: 1 streaming video file (15 min.) :,sd., col.

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